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PLAC Test

PLAC® Test
The Test for Lp-PLA2
 

PLACFacts

The PLAC® Test is the only blood test cleared by the FDA to aid in assessing risk for both coronary heart disease and ischemic stroke associated with atherosclerosis.  87% of strokes are ischemic.  Heart attack and stroke are the major leading cause of death in the US1.

Source: CDC, AHA Statistical Update 2007

WHAT IS THE PLAC TEST?

The PLAC Test is a blood test that measures the level of Lp-PLA2, an enzyme associated with the inflammation of your arteries.  Increased levels of Lp-PLA2 increase your risk of having a heart attack or stroke.

HOW IS THE PLAC TEST DIFFERENT FROM OTHER HEART AND STROKE TESTS MY DOCTOR MAY ORDER?

In most adults, cholesterol causes a fatty deposit called plaque to build up in the walls of the arteries.  When these walls become inflamed, your body produces an enzyme called Lp-PLA2.  If the amount of Lp-PLA2 is high, this may indicate that the plaque is more likely to rupture through the inside lining of your artery into your bloodstream, where it may cause a clot that could result in heart attack or stroke.

The PLAC Test can provide you and your doctor with information about the health of your arteries that was not available in the past.

 

WHAT DO MY TEST RESULTS MEAN?

LOW RISK

BORDERLINE RISK

HIGH RISK

Lp-PLA2 less than 200 ng/mL

Lp-PLA2  = 200 ng/mL

Lp-PLA2 greater than 235 ng/mL

IF YOUR PLAC TEST IS HIGH, YOU ARE AT INCREASED RISK FOR HEART ATTACK OR STROKE.

Now is the time to work with your doctor.  Your doctor may prescribe lifestyle changes, such as exercise or diet.  Your doctor may also order prescription medication, or medicine you can buy without a prescription. 

Remember, your arteries do not hurt when they are inflamed---you may have problems without knowing it.  Over 50% of people who have a heart attack or stroke have no symptoms until the heart attack or stroke occurs.

It is important that you follow your doctor’s directions!  Following the treatment plan your doctor recommends can significantly reduce your risk of a heart attack or stroke.

IF YOUR PLAC TEST IS LOW, YOU ARE AT LOWER RISK FOR HEART ATTACK OR STROKE.

In a study from the Mayo Clinic, 95% of individuals who had Lp-PLA2  levels below 200 ng/mL did not have either a heart attack or stroke over a 4 –year period, even though they had coronary artery disease.

HOW DO I PREPARE FOR THE TEST?

There is no preparation required.  The test just requires the drawing of a tube of blood.  You don’t need to fast and it is OK to have the test done if you are taking medication.

HOW CAN I GET THE PLAC TEST DONE AT OKLAHOMA HEART HOSPITAL?

Outpatient Laboratory services are available at Oklahoma Heart Hospital Monday through Friday from 7:30 a.m. – 5:00 p.m.

Oklahoma Heart Hospital is located at 4050 West Memorial Rd., Oklahoma City, Oklahoma. The Outpatient Laboratory Service is located on the 2nd Floor of Oklahoma Heart Hospital.

No appointment is necessary.

WHO PAYS FOR THE PLAC TEST?

Because this test is new, Medicare and health insurance plans may or may not reimburse for the PLAC Test.

You will need to pay out-of-pocket for the test ($50) and you will be refunded any amount of money that Medicare or insurance reimburses.

HOW DO I RECEIVE MY PLAC TEST RESULTS?

            Oklahoma Heart Hospital will mail your PLAC Test results to you in about a week.

CAN I CONTACT SOMEONE AT OKLAHOMA HEART HOSPITAL IF I HAVE QUESTIONS ABOUT THE PLAC TEST?

            Call 405.608.1465

HOW CAN I GET MORE INFORMATION ABOUT Lp-PLA2   AND THE PLAC TEST?

You can read more about the PLAC® Test and Lp-PLA2   at www.plactest.com

PLAC is a registered trademark of diaDexus, Inc.